Antabuse, or disulfiram, works by inhibiting the enzyme aldehyde dehydrogenase (ALDH).
This enzyme is crucial for metabolizing acetaldehyde, a toxic byproduct of alcohol breakdown. By blocking ALDH, Antabuse causes acetaldehyde to accumulate in the body.
This accumulation produces unpleasant side effects like nausea, vomiting, flushing, and headache when alcohol is consumed.
These reactions act as a deterrent to drinking alcohol. The severity of these effects varies depending on factors such as individual metabolism and the amount of alcohol consumed. Always consult your doctor for personalized guidance.
| Nausea | Feeling sick to your stomach. |
| Vomiting | Throwing up. |
| Flushing | Reddening of the skin, especially in the face and neck. |
| Headache | Pain in the head. |
Antabuse therapy requires strict adherence to avoid alcohol consumption. Your healthcare provider can explain the medication’s use, potential interactions, and precautions thoroughly.
