Cialis: A Comprehensive Overview of its Mechanism

Cialis, also known as tadalafil, works by inhibiting a specific enzyme called phosphodiesterase-5 (PDE5).

This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP) in the smooth muscles of the penis.

    Higher cGMP levels relax these muscles. Relaxation improves blood flow to the penis. This enhanced blood flow facilitates erection.

The effect is triggered by sexual stimulation; Cialis doesn’t cause erections without sexual arousal.

Tadalafil’s long half-life allows for a sustained effect, typically lasting up to 36 hours. This is significantly longer than other similar medications.

This longer duration provides greater flexibility in timing sexual activity. It’s absorbed quickly after oral administration. Metabolism primarily occurs in the liver.

Individual responses vary; factors like age, overall health, and other medications can influence its effects. Always consult your doctor before using Cialis or any medication.

Potential side effects include headache, flushing, nasal congestion, and indigestion. Severe side effects are rare but require immediate medical attention.

Remember to follow your doctor’s prescribed dosage and instructions precisely. Improper use can lead to adverse reactions.