Sildenafil 20mg enhances blood flow to the penis. This happens because it inhibits an enzyme called phosphodiesterase-5 (PDE5). PDE5 normally breaks down cGMP, a molecule crucial for relaxing the smooth muscles in the penis. By blocking PDE5, sildenafil increases cGMP levels, leading to vasodilation–widening of blood vessels. This increased blood flow allows for a firmer erection during sexual stimulation.
Understanding the Mechanism
The process starts with sexual stimulation. This stimulation triggers the release of nitric oxide (NO), initiating a chain reaction that results in increased cGMP. Sildenafil’s action ensures that cGMP levels remain high, sustaining the vasodilation necessary for achieving and maintaining an erection. It’s important to remember that sildenafil doesn’t cause erections without sexual stimulation; it simply enhances the body’s natural response.
Dosage and Considerations
20mg is a common starting dose. Your doctor will determine the appropriate dosage based on individual needs and health conditions. It’s crucial to follow your doctor’s instructions carefully. Side effects, though generally mild, can include headache, flushing, and nasal congestion. Always consult a healthcare professional before starting any medication, especially if you have pre-existing health issues such as heart problems or eye conditions.
